Content


 
Heparin Media

Articles of interest


Heparin Structure/Structural Analysis

  • An heparin dodecasaccharide, containing two contiguous antithrombin binding sequences, have been described and characterized for the first time.

http://www.jbc.org/content/early/2013/07/10/jbc.M113.4852

 

  • HSQC correlation spectroscopy (HSQCcos) can extract chemically related signals from information-rich spectra obtained from complex mixtures such as heparin.

http://pubs.acs.org/doi/abs/10.1021/ac4014379 

 

Analytical Methods

  • Rapid pyrolysis is integrated with direct analysis in real time (DART) mass spectrometry to rapidly screen major glycosaminoglycans, including: heparin, chondroitin sulfate A, dermatan sulfate, and OSCS

http://pubs.acs.org/doi/abs/10.1021/ac401318q 

 

Heparin and Cancer

  • Heparin treatment attenuates tumor metastasis in mice by inhibiting P-selectin-mediated interactions of platelets with carcinoma cell-surface mucin ligands.

http://www.pnas.org/content/98/6/3352.full 

 

 

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